Alafosfalin
Appearance
![]() | |
Names | |
---|---|
IUPAC name
((1R)-1-(((2S)-2-Aminopropanoyl)amino]ethyl)phosphonic acid
| |
Other names
Alaphosphin
| |
Identifiers | |
3D model (JSmol)
|
|
ChemSpider | |
ECHA InfoCard | 100.056.675 |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C5H13N2O4P | |
Molar mass | 196.143 g·mol−1 |
Melting point | 295–297 °C (563–567 °F; 568–570 K) (decomp) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Alafosfalin, also known as alaphosphin, is an phosphonodipeptide with antibacterial[1] and antifungal[2] properties.
References
[edit]- ^ Atherton, Frank R.; Hassall, Cedric H.; Lambert, Robert W. (January 1986). "Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid". Journal of Medicinal Chemistry. 29 (1): 29–40. doi:10.1021/jm00151a005. PMID 3510298.
- ^ Khomutov, Radii M.; Osipova, Tatyana I.; Khurs, Elena N.; Dzhavakhiya, Vitalii G. (November 2008). "Synthesis of alafosfalin and its phosphinic analogue and their fungicidal activity". Mendeleev Communications. 18 (6): 295–296. doi:10.1016/j.mencom.2008.11.001.