Almokalant

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Almokalant
Almokalant.svg
Systematic (IUPAC) name
4-(3-{Ethyl[3-(propane-1-sulfinyl)propyl]amino}-2-hydroxypropoxy)benzonitrile
Identifiers
CAS Number 123955-10-2 YesY
ATC code None
PubChem CID 3033962
ChemSpider 2298526 YesY
UNII I9NG89L275 YesY
ChEMBL CHEMBL362103 YesY
Chemical data
Formula C18H28N2O3S
Molar mass 352.5 g/mol
  (verify)

Almokalant is drug used to treat arrhythmia.[1] It is a potassium channel blocker. It has been found to have teratogenic effects in rats.[2]

References[edit]

  1. ^ Wiesfeld AC, Crijns HJ, Bergstrand RH, Almgren O, Hillege HL, Lie KI (1993). "Torsades de pointes with Almokalant, a new class III antiarrhythmic drug". American Heart Journal 126 (4): 1008–1011. doi:10.1016/0002-8703(93)90726-p. 
  2. ^ Wellfelt, K.; Sköld, A. C.; Wallin, A.; Danielsson, B. R. (1999-04-01). "Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species". Reproductive Toxicology (Elmsford, N.Y.) 13 (2): 93–101. ISSN 0890-6238. PMID 10213516.