3D model (JSmol)
|Molar mass||136.15 g·mol−1|
|Melting point||−1 °C (30 °F; 272 K)|
|Boiling point||248 °C (478 °F; 521 K)|
|Flash point||108 °C (226 °F; 381 K)|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
4-Anisaldehyde (p-anisaldehyde, anisic aldehyde, or anise aldehyde) is an organic compound that is commonly encountered in fragrances, both synthetic and natural. The compound consists of a benzene ring with an aldehyde and a methoxy group. It is a clear liquid with a strong aroma. Two related isomers, ortho-anisaldehyde and meta-anisaldehyde, are also known but less commonly encountered. It provides sweet, floral and strong aniseed odor.
Anisaldehyde is prepared commercially by oxidation of methoxytoluene (p-cresyl methyl ether) using manganese dioxide. It can also be produced by oxidation of anethole, a related fragrance that is found in some alcoholic beverages.
Being structurally related to vanillin, anisaldehyde is a widely used in the fragrance and flavor industry. Anisaldehyde is used as an intermediate in the synthesis of other compounds important in pharmaceuticals and perfumery. ortho-Anisaldehyde has a scent of licorice.
A solution of para-anisaldehyde in acid and ethanol is a useful stain in thin layer chromatography. Different chemical compounds on the plate can give different colors, allowing easy distinction.
Drugs made from 4-Anisaldehyde include:
- PMA & PMMA
- Meobentine (via p-methoxybenzylamine made via reduction of the oxime).
- Merck Index, 11th Edition, 693
- "p-Anisaldehyde". Sigma-Aldrich.
- Karl-Georg Fahlbusch, Franz-Josef Hammerschmidt, Johannes Panten, Wilhelm Pickenhagen, Dietmar Schatkowski, , Kurt Bauer, Dorothea Garbe and Horst Surburg "Flavors and Fragrances" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2003. doi:10.1002/14356007.a11_141
- Stains for Developing TLC Plates