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Antiamoebin

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This is an old revision of this page, as edited by DePiep (talk | contribs) at 22:37, 24 June 2015 (Chembox: change Autoignition into A'tionPt. remove/replace depecated params. simplify ws. (via AWB script)). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Antiamoebin
Names
IUPAC name
2-[[(4S)-1-[2-[2-[[2-[[2-[[(2R)-2-[[2-[2-[2-[(2-acetamido-3-phenylpropanoyl)-methylamino]propanoyl-methylamino]propanoyl-methylamino]acetyl]amino]-2-methylbutanoyl]amino]acetyl]amino]-4-methylpentanoyl]-methylamino]propanoyl-methylamino]acetyl]-4-hydroxypyrrolidine-2-carbonyl]amino]-N-[(2R)-1-[(4S)-4-hydroxy-2-[[1-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]-methylcarbamoyl]pyrrolidin-1-yl]-2-methyl-1-oxobutan-2-yl]pentanediamide
Identifiers
3D model (JSmol)
  • CC[C@](C)(C(=O)NCC(=O)NC(CC(C)C)C(=O)N(C)C(C)C(=O)N(C)CC(=O)N1C[C@H](CC1C(=O)NC(CCC(=O)N)C(=O)N[C@](C)(CC)C(=O)N2C[C@H](CC2C(=O)N(C)C(C)C(=O)N3CCCC3C(=O)N[C@@H](CC4=CC=CC=C4)CO)O)O)NC(=O)CN(C)C(=O)C(C)N(C)C(=O)C(C)N(C)C(=O)C(CC5=CC=CC=C5)NC(=O)C
Properties
C80H123N17O20
Molar mass 1642.963 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Antiamoebin is an anti-microbial/protozoan polypeptide of fungal origin.

  • Nagaraj, G.; Uma, MV.; Shivayogi, MS.; Balaram, H. (January 2001). "Antimalarial activities of peptide antibiotics isolated from fungi". Antimicrobial Agents and Chemotherapy. 45 (1). NCBI: 145–9. doi:10.1128/aac.45.1.145-149.2001. PMC 90252. PMID 11120957.
  • Duclohier, H. (June 2007). "Peptaibiotics and peptaibols: an alternative to classical antibiotics?". Chem Biodivers. NCBI. pp. 1023–6. doi:10.1002/cbdv.200790094. Retrieved 15 December 2013.