Despite being active during the day, Azara's agoutis are quite difficult to study, as they are naturally extremely shy and will flee and hide when humans approach. Their shyness may be related to their solitary lifestyles, but may be because they are heavily preyed upon by many carnivorous species, including humans. However, if bred in captivity, they can become trusting animals. Azara's agoutis will let out little barks when alarmed. These animals are sometimes known as "jungle gardeners", as they often bury nuts and seeds and forget where they put them, therefore helping new plants to grow.