B25, B-25 or B.25 may refer to:
- B-25 Mitchell, an American aircraft which saw service during World War II
- Blackburn B-25, a 1939 British Fleet Air Arm fighter aircraft
- B-25, a guitar model in the Gibson B series
- B25, a bus route on the Fulton Street Line (Brooklyn surface)
- B.25, Guthrie code for the Kota language (Gabon)
- 25 amp, type B – a standard circuit breaker current rating
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