Benzamidine

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Benzamidine
Skeletal formula
Ball-and-stick model
Names
IUPAC name
Benzenecarboximidamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.009.589 Edit this at Wikidata
KEGG
  • InChI=1S/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9) checkY
    Key: PXXJHWLDUBFPOL-UHFFFAOYSA-N checkY
  • InChI=1/C7H8N2/c8-7(9)6-4-2-1-3-5-6/h1-5H,(H3,8,9)
    Key: PXXJHWLDUBFPOL-UHFFFAOYAU
  • [N@H]=C(N)c1ccccc1
Properties
C7H8N2
Molar mass 120.15 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Benzamidine is a reversible competitive inhibitor of trypsin, trypsin-like enzymes and serine proteases.

It is often used as a ligand in protein crystallography to prevent proteases from degrading a protein of interest; the triangular diamine group at the bottom gives it a very obvious 'stick-man' shape which shows up in difference density maps.

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