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A binding domain is a protein domain which binds to a specific atom or molecule, such as calcium or DNA. Protein Domain is a part of a protein sequence and a tertiary structure that can change, function, and live by itself for the rest of the protein chain. (Phillips 1). Upon binding, proteins may undergo a conformational change. Binding domains are essential for the function of many proteins. They are essential because they help splice, assemble, and translate proteins. (Yong 1).
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1. Phillips DC. (1966). "The three-dimensional structure of an enzyme molecule". Scientific
American. 215 (5): 78–90. doi:10.1038/scientificamerican1166-78.
2. Yong, J., T. J. Golembe, D. J. Battle, L. Pellizzoni, and G. Dreyfuss. "SnRNAs Contain
Specific SMN-binding Domains That Are Essential for SnRNP Assembly."
Molecular and Cellular Biology. U.S. National Library of Medicine, Apr. 2004.
Web. 06 Apr. 2017.