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Brandywine Creek may refer to:
- Brandywine Creek (British Columbia), a tributary of the Cheakamus River
- Brandywine Creek (Big Blue River), in Indiana
- Brandywine Creek (Broken Sword Creek), Crawford County, Ohio
- Brandywine Creek (Cuyahoga River), in Summit County, Ohio
- Brandywine Creek (Quittapahilla Creek), in Lebanon County, Pennsylvania
- Brandywine Creek (Christina River), in Chester County, Pennsylvania and New Castle County, Delaware
- Brandywine Creek State Park, in New Castle County, Delaware
- Brandywine (disambiguation)
- Baranduin or Brandywine River, a river in Middle-earth in the fiction of J. R. R. Tolkien
|This disambiguation page lists articles associated with the title Brandywine Creek.
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