Ethylene bis(iodoacetate)

Ethylene bis(iodoacetate)
Names
	Preferred IUPAC name Ethane-1,2-diyl bis(iodoacetate)
	Other names Ethane-1,2-diyl bis(2-iodoacetate); S-10
Identifiers
CAS Number	5451-51-4 ;
3D model (JSmol)	Interactive image;
ChemSpider	20296;
PubChem CID	21594;
UNII	29S4W5JLV7 ;
CompTox Dashboard (EPA)	DTXSID20202923;
	InChI InChI=1S/C6H8I2O4/c7-3-5(9)11-1-2-12-6(10)4-8/h1-4H2 Key: KBCCFFGCRDUANG-UHFFFAOYSA-N;
	SMILES C(COC(=O)CI)OC(=O)CI;
Properties
Chemical formula	C6H8I2O4
Molar mass	397.935 g·mol−1
Hazards
	Lethal dose or concentration (LD, LC):
LD50 (median dose)	16.1 mg/kg (mice, intraperitoneal); 4.94 mg/kg (dogs, intravenous)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Ethylene bis(iodoacetate), also known as S-10, is the iodoacetate ester of ethylene glycol. It's an alkylating agent that has been studied as an anticancer drug.^[1]

References

^ "Enzyme Alterable Alkylating Agents. VI. Synthesis, Chemical Properties, Toxicities, and Clinical Trial of Haloacetates and Haloacetamides Containing Enzyme-Susceptible Bonds". JNCI: Journal of the National Cancer Institute. August 1963. doi:10.1093/jnci/31.2.297.

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