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CGB7

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CGB7
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
AliasesCGB7, CG-beta-a, CGB6, chorionic gonadotropin beta subunit 7, chorionic gonadotropin subunit beta 7
External IDsOMIM: 608826; HomoloGene: 113799; GeneCards: CGB7; OMA:CGB7 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_033142
NM_001385261

n/a

RefSeq (protein)

NP_000728.1
NP_149032.1
NP_149133.1
NP_149439.1
NP_149133

n/a

Location (UCSC)Chr 19: 49.05 – 49.06 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Choriogonadotropin subunit beta is a protein that in humans is encoded by the CGB7 gene.[3][4]

This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 7 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and a unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene.[4]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196337Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Policastro P, Ovitt CE, Hoshina M, Fukuoka H, Boothby MR, Boime I (Nov 1983). "The beta subunit of human chorionic gonadotropin is encoded by multiple genes". J Biol Chem. 258 (19): 11492–9. doi:10.1016/S0021-9258(17)44254-2. PMID 6194155.
  4. ^ a b "Entrez Gene: CGB7 chorionic gonadotropin, beta polypeptide 7".
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Further reading

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