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Cantharidic acid

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Cantharidic acid
Clinical data
ATC code
  • none
Identifiers
  • 2,3-dimethyl-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylic acid
CAS Number
ChEBI
ChEMBL
ECHA InfoCard100.164.462 Edit this at Wikidata
Chemical and physical data
FormulaC10H14O5
Molar mass214.217 g·mol−1

Cantharidic acid is a selective inhibitor of PP2A (protein phosphatase 2) and PP1 (protein phosphatase 1).[1][2]

It is the hydrolysis product of cantharidin.

See also

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References

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  1. ^ "Cantharidic Acid | CAS 28874-45-5".
  2. ^ Azoulay-Alfaguter I, Strazza M, Peled M, Novak HK, Muller J, Dustin ML, Mor A (August 2017). "The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse". Science Signaling. 10 (491): eaal2880. doi:10.1126/scisignal.aal2880. PMC 9437928. PMID 28790195. S2CID 4886031.