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Hydrogen peroxide–urea

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Hydrogen peroxide–urea
Clinical data
Routes of
administration
topical (teeth or mouth)
Identifiers
  • hydrogen peroxide; urea
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.004.275 Edit this at Wikidata
Chemical and physical data
FormulaCH6N2O3
Molar mass94.07 g·mol−1 g·mol−1

Carbamide peroxide, also called urea peroxide, urea hydrogen peroxide, and percarbamide, is an oxidising agent, consisting of hydrogen peroxide compounded with urea. The molecular formula is CH6N2O3, or CH4N2O.H2O2. It is a white crystalline solid that releases oxygen in contact with water.

The chemical is a skin, eye and respiratory irritant. It is also corrosive and causes burns. It doesn't hurt at 10% concentration (3% hydrogen peroxide equivalent) but it might hurt at 35% (12% equivalent), causing white chemical burns on skin and gums alike.

Pure carbamide peroxide has the form of white crystals or crystal powder, is slightly soluble in water (0.05 g/mL)[1], and contains approximately 35% hydrogen peroxide.

Uses

Carbamide peroxide is used to

Carbamide peroxide is commonly encountered in cosmetic dentistry, where it is used to "bleach" teeth. The active ingredient is hydrogen peroxide, which acts to oxidise interprismatic extrinsic staining within tooth enamel. There are several methods of applying the peroxide gel to the tooth ranging from night-guard application at home or in-surgery application. The bleaching obtained is proportional to the length of time the peroxide is applied to the tooth, and the concentration used. The concentration most commonly used for tooth whitening purposes is 15%.

A 10% solution in glycerol is used to treat ulcers and other lesions in the mouth.

A 6.5% concentration solution is used to loosen and remove earwax.

References

  1. ^ Sigma-Aldrich specification sheet
  2. ^ "A CLINICAL EVALUATION OF CARBAMIDE PEROXIDE AND HYDROGEN PEROXIDE WHITENING AGENTS DURING DAYTIME USE". American Dental Association.
  3. ^ Toothwhitening from the UMD of New Jersey website
  4. ^ a b Center for Integrative Medicine: Carbamide Peroxide from the University of Maryland Medical Center website