Carol Lynn Curchoe
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|Carol Lynn Curchoe|
Governor Gary R. Herbert and Carol Lynn Curchoe, Ph.D. Utah State Science Advisor
|Native name||Carol Lynn Curchoe|
|Born||1979 (age 36–37)
|Fields||Stem cell research, cloning, epigenetics|
|Alma mater||University of Connecticut, Sanford-Burnham Medical Research Institute|
|Thesis||Epigenetic reprogramming in cloned livestock (2006)|
|Known for||Former Utah State Science Advisor|
Carol Lynn Curchoe (born in 1979 in Manchester, Connecticut) is an American reproductive biologist specializing in molecular and cellular biology and biotechnology. Her key contributions to those fields include advances in stem cell culture, epigenetics and reprogramming. She is the former Utah State Science Advisor, President and CEO of 32ATPs, an adjunct biology faculty at Utah Valley University, and an author of personal essay and fiction.
Carol Lynn Curchoe is the former Utah State Science Advisor to Governor Gary R. Herbert. She was responsible for a number of statewide scientific initiatives, including the Utah State STEM Action Center, Governor's Medals for Science and Technology, Work Ready Utah powered by ACT, and other workforce and advanced manufacturing initiatives.
As an undergraduate researcher, Curchoe was part of a team that characterized the meat and milk composition of bovine clones that informed the Food and Drug Administration’s (FDA) decision about these products for general consumption. Her dissertation research, performed at the University of Connecticut in the Physiology of Reproduction, and completed in three years, was one of the fastest graduate degrees ever earned at Uconn. That work characterized the reprogramming of imprinted genes, such as IGF2, IGF2R, and H19 in cloned livestock.
Her California Institute of Regenerative Medicine postdoctoral work was performed at the Sanford Burnham Medical Research Institute in the field of human embryonic stem cell culture where she developed a protocol for the production of hESC derived neural precursors and peripheral neurons, specifically for therapeutic use. Additionally, she developed an in vitro model of early human neurulation events.
After finishing her academic research she entered into business development as an associate at Burnham where she was part of a team that strengthened translational research by establishing clinical research partnerships with Pfizer, Takeda, and Johnson & Johnson. In 2010 she helped to launch the Office of Collaborative Science at the NYU Langone School of Medicine, which unified 17 disparate fee for service labs. Best practice models for tracking core-contributed publications resulted. Subsequently, she founded 32ATPs, an international scientific business and management consulting firm in 2011, and in 2014 32ATPs opened a clean energy research and development branch. As a Utah Valley University adjunct faculty she taught mammalian cloning and biotechnology using project based learning, inverted classrooms, and community building through social media. She is the author of the Wastach Iron Pen award winning short story "In Bloom".
Curchoe is known to actively mentor women researchers, staff members and students who are just getting interested in a career in science. She credits the mentorship she received working in the laboratory of Dr. X. Cindy Tian for being able to earn a graduate degree after dropping out of high school. Since relocating to Utah she has been involved with community initiatives such as Latinos in Action, Expanding Your Horizons, Salt Lake Valley Science and Engineering Fair, FIRST and many others.
Curchoe was born in Connecticut, of French Canadian descent (Fournier family lineage), the second child of Cora Hall and Richard Curchoe. She has four siblings; sisters, Kelly and Denise and brothers, Jason and Christopher, and numerous nieces and nephews. Curchoe earned an Associate of Science degree at Manchester Community College, a bachelor's degree, master’s degree, and Ph.D. at the University of Connecticut, and performed her postdoctoral research at Sanford-Burnham Institute for Medical Research as a California Institute for Regenerative Medicine funded postdoctoral scholar.
Honors and awards
- Utah Business Magazine's 40 Under 40 Award, 2014
- Appointed to the Office of the State Science Advisor by Governor Gary R. Herbert, 2013
- Wasatch Iron Pen, 2013
- First Runner Up Fishman Award, 2009
- Presidents Doctoral Dissertation Award, 2006
- Environmental Leadership Award Finalist, 2005
- Second Runner Up, Poster, Second Annual Asian Reproductive Biology Conference, 2005
- Student Life Award Finalist, 2005
- Fisher Scientific Trainee Award, 2003
- Tian, X. C.; Kubota, C.; Sakashita, K.; Izaike, Y.; Okano, R.; Tabara, N.; Curchoe, C.; Jacob, L.; Zhang, Y.; Smith, S.; Bormann, C.; Xu, J.; Sato, M.; Andrew, S.; Yang, X. (2005). "Meat and milk compositions of bovine clones". Proceedings of the National Academy of Sciences. 102 (18): 6261–6. doi:10.1073/pnas.0500140102. PMC . PMID 15829585.
- Curchoe, C.; Zhang, S; Bin, Y; Zhang, X; Yang, L; Feng, D; O'Neill, M; Tian, XC (2005). "Promoter-Specific Expression of the Imprinted IGF2 Gene in Cattle (Bos taurus)". Biology of Reproduction. 73 (6): 1275–81. doi:10.1095/biolreprod.105.044727. PMID 16120826.
- Suteevun-Phermthai, T.; Curchoe, C.L.; Evans, A.C.; Boland, E.; Rizos, D.; Fair, T.; Duffy, P.; Sung, L.Y.; Du, F.; Chaubal, S.; Xu, J.; Wechayant, T.; Yang, X.; Lonergan, P.; Parnpai, R.; Tian, X.C. (2009). "Allelic switching of the imprinted IGF2R gene in cloned bovine fetuses and calves". Animal Reproduction Science. 116 (1–2): 19–27. doi:10.1016/j.anireprosci.2009.01.003. PMID 19217227.
- Curchoe, Carol Lynn; Zhang, Shouquan; Yang, Lan; Page, Raymond; Tian, X. Cindy (2009). "Hypomethylation trends in the intergenic region of the imprinted IGF2 and H19 genes in cloned cattle". Animal Reproduction Science. 116 (3–4): 213–25. doi:10.1016/j.anireprosci.2009.02.008. PMID 19282114.
- Li*, Chao; Bin, Yanfang; Curchoe, Carol; Yang, Lan; Feng, Dingyuan; Jiang, Qingyan; O'Neill, Michael; Tian, X. Cindy; Zhang, Shouquan (2008). "Genetic Imprinting ofH19andIGF2in Domestic Pigs (Sus scrofa)". Animal Biotechnology. 19 (1): 22–7. doi:10.1080/10495390701758563. PMID 18228173.
- Tian, XC; Smith, SL; Zhang, SQ; Kubota, C; Curchoe, C; Xue, F; Yang, L; Du, F; Sung, LY; Yang, X (2007). "Nuclear reprogramming by somatic cell nuclear transfer--the cattle story". Society of Reproduction and Fertility supplement. 64: 327–39. PMID 17491157.
- Cimadamore, Flavio; Curchoe, Carol Lynn; Alderson, Nazilla; Scott, Fiona; Salvesen, Guy; Terskikh, Alexey V. (2009). "Nicotinamide Rescues Human Embryonic Stem Cell-Derived Neuroectoderm from Parthanatic Cell Death". Stem Cells. 27 (8): 1772–81. doi:10.1002/stem.107. PMID 19544437.
- Curchoe, Carol Lynn; Maurer, Jochen; McKeown, Sonja J.; Cattarossi, Giulio; Cimadamore, Flavio; Nilbratt, Mats; Snyder, Evan Y.; Bronner-Fraser, Marianne; Terskikh, Alexey V. (2010). Najbauer, Joseph, ed. "Early Acquisition of Neural Crest Competence During hESCs Neuralization". PLoS ONE. 5 (11): e13890. doi:10.1371/journal.pone.0013890. PMC . PMID 21085480.
- Curchoe, Carol Lynn; Russo, Joseph; Terskikh, Alexey V. (2012). "HESC derived neuro-epithelial rosettes recapitulate early mammalian neurulation events; an in vitro model". Stem Cell Research. 8 (2): 239–46. doi:10.1016/j.scr.2011.11.003. PMID 22265743.
- Loomis, CA; Curchoe, CL (2012). "Method for tracking core-contributed publications". J Biomol Tech. 23: 122–7. doi:10.7171/jbt.12-2304-003. PMC . PMID 23204927.
- 2009 CIRM Annual Report Cover
- A Day In the Life (Personal Essay)
- Ordinary Science, Extraordinary Opinions
- Search Results for author Curchoe CL on PubMed.
- Wasatch Iron Pen
- FDA- Animal Cloning A Risk Assessment
- Office of the State Science Advisor
- Mammalian Cloning, Biotech 409R, Utah Valley University
- Business Tips
- Inventions that Changed the World- PCR
- Building a STEM Literate State