Chemoprotective agent

From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by BG19bot (talk | contribs) at 04:18, 14 October 2016 (WP:CHECKWIKI error fix for #03. Missing Reflist. Do general fixes if a problem exists. -). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

In the treatment of cancer, chemoprotective agents are drugs which protect healthy tissue from the toxic effects of anticancer drugs.

Examples[1][2] include:

  • Amifostine, approved by the FDA in 1995, which helps prevent kidney damage in patients undergoing cisplatin and carboplatin chemotherapy
  • Mesna, approved by the FDA in 1988, which helps prevent hemorrhagic cystitis (bladder bleeding) in patients undergoing cyclophosphamide or ifosfamide chemotherapy
  • Dexrazoxane, approved by the FDA in 1995, which helps prevent heart problems in patients undergoing doxorubicin chemotherapy

References

  1. ^ Cancer, Cleveland Clinic. "Chemoprotective Agents: Amifostine, Mesna, Dexrazoxane - What is Chemotherapy? - Chemocare". chemocare.com. Retrieved 2016-10-13.
  2. ^ First Aid for the USMLE Step 1 2016. ISBN 9781259587375.

External links

Public Domain This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.