Cobalt-precorrin-5B (C1)-methyltransferase
| Cobalt-precorrin-5B (C1)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.195 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Cobalt-precorrin-5B (C1)-methyltransferase (EC 2.1.1.195, cobalt-precorrin-6A synthase, CbiD (gene)) is an enzyme with system name S-adenosyl-L-methionine:cobalt-precorrin-5B (C1)-methyltransferase.[1][2] This enzyme catalyses the following chemical reaction
This enzyme catalyses the C-1 methylation of cobalt-precorrin-5B in the anaerobic pathway of adenosylcobalamin biosynthesis.
References
- ^ Roper, J.M., Raux, E., Brindley, A.A., Schubert, H.L., Gharbia, S.E., Shah, H.N. and Warren, M.J. (2000). "The enigma of cobalamin (Vitamin B12) biosynthesis in Porphyromonas gingivalis. Identification and characterization of a functional corrin pathway". J. Biol. Chem. 275 (51): 40316–40323. doi:10.1074/jbc.M007146200. PMID 11007789.
{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link) - ^ Roessner, C.A., Williams, H.J. and Scott, A.I. (2005). "Genetically engineered production of 1-desmethylcobyrinic acid, 1-desmethylcobyrinic acid a,c-diamide, and cobyrinic acid a,c-diamide in Escherichia coli implies a role for CbiD in C-1 methylation in the anaerobic pathway to cobalamin". J. Biol. Chem. 280 (17): 16748–16753. doi:10.1074/jbc.M501805200. PMID 15741157.
{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
External links
- Cobalt-precorrin-5B+(C1)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)