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- Cristóbal Colón, the Spanish language name for the Italian explorer Christopher Columbus (1451-1506)
- Bartolo Colón (born 1973), Dominican baseball pitcher
- Carlos Colón, musician, member of The Deadlines
- Carlos Colón, Sr. (born 1948), Puerto Rican wrestler
- Carly Colón (born 1979), Puerto Rican wrestler, son of Carlos Colón, Sr.
- Christian Colón (born 1989), Puerto Rican baseball infielder
- Eddie Colón (born 1982), Puerto Rican wrestler, son of Carlos Colón, Sr.
- Ernie Colón (1931–2019), American comics artist
- Kristiana Rae Colón (born 1986), American poet and playwright
- Orlando Colón (born 1982), Puerto Rican wrestler, nephew of Carlos Colón, Sr.
- Willie Colón (born 1950), Puerto Rican American salsa musician
|surname Colón. If an internal link intending to refer to a specific person led you to this page, you may wish to change that link by adding the person's given name(s) to the link.This page lists people with the|