Constantin von Monakow

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Constantin von Monakow

Constantin von Monakow (November 4, 1853 – October 19, 1930) was a Russian-Swiss neuropathologist who was a native of Bobretsovo in the Vologda Governorate.

He studied at the University of Zurich while working as an assistant at the Burghölzli Institute under the directorship of Eduard Hitzig (1839-1907). After graduation, he was an assistant at St. Pirminsberg, where he performed scientific investigations of cerebral anatomy. In 1885 he returned to Zurich, where he later became director of the brain anatomy institute. In 1917 he founded the Schweizer Archiv für Neurologie und Psychiatrie (Swiss Archives of Neurology and Psychiatry), and was its editor-in-chief until his death. He died in Zurich in 1930.

Neuropathological research[edit]

Monakow made numerous contributions in his analysis of the sensory and motor pathways of the brain. He was interested in the functional relationships amongst the different regions of the brain, and conceptualized that in faculties such as intellect, coordination was needed among its many diverse parts.[1] From his brain research, he introduced the terms "chronogenic localization" and "diaschisis".

In 1914 Monakow coined the term "diaschisis" to describe how an injury to the brain can create behavioral deficiencies that may be followed by eventual recovery. The word is derived from Greek, meaning "shocked throughout". He believed the brain to exist as a delicate balance between its different components, and if a component became disturbed through injury it could affect other parts of the brain not seemingly associated with the site of injury. Therefore, if the damage wasn't too severe, functional behaviour would recover once the period of diaschisis wore off.

He name is lent to "Monakow's nucleus" (lateral cuneate nucleus)[2] and to the "bundle of Monakow" (rubrospinal fasciculus). In addition, "Monakow's syndrome" bears his name, defined as contralateral hemiplegia, hemianaesthesia and homonomous hemianopsia due to occlusion of the anterior choroidal artery.[3]

He was responsible for identifying the arcuate fasciculus as the fibre tract that connected the Broca's and Wernicke's speech areas. This anatomical link (which is now questioned)[4] “soon became a dogma in neurology and still today provides the backbone of anatomical models of language.”[4]

Selected writings[edit]

  • Pathologie du cerveau, in German as Gehirnpathologie (1897) - Brain pathology.
  • Über Lokalisation der Hirnfunktion (1910) - On localization of brain function.
  • La localisation de l'encephale et la dégradation fonctionelle par des lésions circonscrites du cortex cérébral, in German as Die Lokalisation im Grosshirn und Abbau der Funktion durch kortikale Herde (1914) - Localization in the cortex and the reduction of cortical function.
  • Gefuhl, Gesittung und Gehirn, (1916) - Feeling, morality and the brain.
  • Psychiatrie und Biologie, (1919) = Psychology and biology.
  • Schizophrenie und Plexus chorioidei (with Kitabayashi), 1919 - Schizophrenia and the choroid plexus.

References[edit]

  1. ^ [1] Origins of Neuroscience, A History of Explorations Into Brain Function by Stanley Finger
  2. ^ Medilexicon Accessory cuneate nucleus
  3. ^ [2] Mondofacto Dictionary, definition of eponym
  4. ^ a b Catani M, Mesulam M. (2008). The arcuate fasciculus and the disconnection theme in language and aphasia: history and current state. Cortex. 44(8):953-61. PMID 18614162

External links[edit]