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Contactins are a subgroup of molecules belonging to the immunoglobulin superfamily that are expressed exclusively in the nervous system. The subgroup consists of six members now referred to as contactin 1-6,[1] but historically they had different names as shown in the table below:

New name Old name
Contactin 1 Contactin
Contactin 2 TAG-1
Contactin 3 BIG-1
Contactin 4 BIG-2
Contactin 5 NB-2
Contactin 6 NB-3


  1. ^ Shimoda, Yasushi; Watanabe, Kazutada (1 January 2009). "Contactins". Cell Adh Migr. 3 (1): 64–70. PMC 2675151Freely accessible. PMID 19262165.