|Different regions of Ileal pouch-anal anastomosis|
|Classification and external resources|
Cuffitis is inflammation at the anal transition zone or “cuff” created as a result of ileal pouch-anal anastomosis (IPAA). It is considered a variant form of ulcerative colitis that occurs in the rectal cuff. Cuffitis is a common complication of IPAA, particularly when a stapled anastomosis without mucosectomy procedure has been used.
Symptoms of cuffitis mimic those of pouchitis. In addition, patients with cuffitis often present with small volume bloody bowel movements. Often, cuffitis can produce the appearance of bright red blood on tissue.
Patients whose cuffitis is refractory to mesalamine and/or corticosteroids should be evaluated for other disease in the cuff area, such as fistula or anastomotic leaks. Cuffitis that is refractory to medication can also be a sign of Crohn's disease of the pouch.
Cuffitis that is refractory, Crohn's-related, or is associated with surgical complications can contribute to pouch failure.
- "Pouchitis: Causes, Symptoms & Treatment | Cleveland Clinic". my.clevelandclinic.org. Retrieved 2016-12-12.
- Shen, Bo (2016-12-12). "Diagnosis and Management of Postoperative Ileal Pouch Disorders". Clinics in Colon and Rectal Surgery. 23 (4): 259–268. doi:10.1055/s-0030-1268252. ISSN 1531-0043. PMC 3134805. PMID 22131896.
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