Coffield studied at Goldsmiths College, Camberwell School of Art and the Slade School of Art in London, where he received his Bachelor's Degree in 1993 in Fine Arts. He has exhibited at venues ranging from the Courtauld Institute, Somerset House to the National Portrait Gallery, London.
In the early 1990s, Coffield worked with Joshua Compston on the formation of Factual Nonsense — the centre of the emerging YBA scene. He subsequently wrote Factual Nonsense: The Art and Death of Joshua Compston, published in 2013.
In 2003, his controversial portrait of Ivan Massow, former chairman of the ICA, in fox hunting attire, was exhibited at the National Portrait Gallery in London. Coffield has painted portraits of Molly Parkin, George Galloway, and Peter Tatchell. Coffield has painted Arthur Scargill using coal dust as a medium, and made protest art prints relating to The Battle of Orgreave.
Coffield lives and works in London.
- Factual Nonsense: The Art and Death of Joshua Compston, 2013
- "Interview with Darren Coffield". Milan: Designboom. 2014-10-27.
- Buck, Louisa (2013-08-14). "Factual Nonsense: The Art And Death of Joshua Compston". London: The Telegraph.
- Roux, Caroline (2003-04-26). "Aspects of me". London: The Guardian Magazine. Retrieved 2008-01-04.
- "Gorgeous George' sits pretty with Blair and Bush". The Guardian. London. 8 November 2006. Retrieved 1 November 2016.
- "Darren Coffield. Ashes and Diamonds". Wall Street International. 2013.
- Battersby, Mathilda (2013-04-13). "From Kate's smiling eyebrows to Harry Styles' staring chin: The topsy turvy faces of celebrity". London: The Independent.