In 1952, with his wife Karen Karnes, Weinrib was a resident potter during the first Crafts Institute at Black Mountain College. Lasting October 15–29, 1952, the workshop also included instruction by Bernard Leach, Shoji Hamada, Dr. Soetsu Yanagi and Marguerite Wildenhain. At this time, Weinrib began experimenting in his practice of art production, creating "tiles, "slab" pottery, and sculpted pots."
In the summer of 1953, Weinrib and Karnes led the school's second Craft Institute along with Warren MacKenzie, Daniel Rhodes, Peter Voulkos. In fall 1954, Weinrib and Karnes would leave Black Mountain College and relocate to Stony Point, New York to begin working with M. C. Richards, David Tudor, and John Cage at Gate Hill Cooperative.
Weinrib is known for working with diverse media. In the 1960s, Weinrib became prominent creating abstract sculptures to be mounted or hung during exhibition in a series of shows at the Howard Wise Gallery. In the 1970s, Weinrib created cast resin sculptural art.
David Weinrib was an adjunct professor at Pratt University  for thirty years. While teaching there, he founded and then curated the school's sculpture garden, The Pratt Sculpture Park. In 2006, Public Art Review named the garden, "one of the ten best college and university campus art collections in the country."
During his career, Weinrib was honored, with "Guggenheim, NEA, and Fulbright grants."
- "David Weinrib (1924- 2016)". Art Forum. Art Forum. Retrieved 10 April 2016.
- Duberman, Martin (1972). Black Mountain: An Exploration in Community. Doubleday: E. P. Dutton & Co., Inc. pp. 362–365. ISBN 0385070594.
- Molesworth, Helen. Leap Before You Look Black Mountain College 1933 - 1957. p. 260. ISBN 9780300211917.
- "Campus Directory". Pratt. Pratt Institute. Retrieved 11 April 2016.
- "Sculpture Park". Pratt. Pratt Institute. Retrieved 11 April 2016.