3D model (JSmol)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
A deflectin is one of a family of antibiotic chemicals produced by Aspergillus deflectus which contain a 6H-furo[2,3-h]-2-benzopyran-6,8(6aH)-dione core.
Deflectins are yellow coloured crystalline substances when pure. They react with ammonia, by replacing an oxygen atom in the six-membered ring with an NH group. They are weak acids. On adding a strong base to an alcoholic solution of deflectin, it show a red colour for a short time. Deflectin 1a contains a 1-oxooctyl side chain. It has a melting point of 161 °C. Deflectin 1b contains a ten carbon side chain and melts at 152 °C. Deflectin 1c has a 12-atom side chain and melts at 141 °C.
Deflectin 2a melts at 122 °C. It has a 10 carbon atom side chain with a 2-methyl branch. Deflectin 2b is similar but the side chain is 2 atoms longer. It melts at 111 °C.
|Deflectin 1a||Deflectin 1b||Deflectin 1c||Deflectin 2a||Deflectin 2b|
- Anke, H.; Kremmer, T.; Ho..fle, G. (August 1981). "Deflectins, New Antimicrobial Azaphilones From Aspergillus deflectus". The Journal of Antibiotics. 34 (8): 923–928. doi:10.7164/antibiotics.34.923. PMID 7319924.
- Bycroft, Barrie W. (1987). Dictionary of Antibiotics & Related Substances. CRC Press. p. 258. ISBN 9780412254505.