Deuterated chloroform
| |||
Names | |||
---|---|---|---|
IUPAC name
Trichloro(2H)methane[citation needed]
| |||
Other names
Chloroform-d
Deuterochloroform | |||
Identifiers | |||
3D model (JSmol)
|
|||
1697633 | |||
ChEBI | |||
ChemSpider | |||
ECHA InfoCard | 100.011.585 | ||
EC Number |
| ||
PubChem CID
|
|||
UN number | 1888 | ||
CompTox Dashboard (EPA)
|
|||
| |||
| |||
Properties | |||
CDCl3 | |||
Molar mass | 120.384 g mol−1 | ||
Density | 1.500 g cm−3 | ||
Melting point | −64 °C (−83 °F; 209 K) | ||
Boiling point | 61 °C (142 °F; 334 K) | ||
Hazards | |||
NFPA 704 (fire diamond) | |||
Related compounds | |||
Related compounds
|
Chloroform | ||
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Deuterated chloroform (CDCl3), also known as chloroform-d, is an isotopologue of chloroform (CHCl3) in which the hydrogen atom ("H") is replaced with a deuterium (heavy hydrogen) isotope ("D"). Deuterated chloroform is the most common solvent used in NMR spectroscopy of organic molecules, because of its ability to dissolve a wide variety of organic molecules. Most compounds soluble in dichloromethane are soluble in chloroform, but chloroform is much cheaper than deuterated DCM.[1]
Properties
The properties of CDCl3 are virtually identical to those of regular chloroform.
NMR spectrum
In proton NMR spectroscopy, the deuterium does not exhibit a large interfering peak, whereas protium (regular hydrogen) shows a large peak in the spectrum. Most commercial chloroform-d, however, contains a small amount of non-deuterated chloroform, often known as the residual; this results in a small singlet at 7.26 ppm. In carbon-13 NMR, the sole carbon deuterated chloroform shows a triplet at a chemical shift of 77 ppm with the three peaks being about equal size, as the deuterium has a spin of 1.[1]