Difluoroacetic acid

Difluoroacetic acid
Names
	Preferred IUPAC name Difluoroacetic acid
	Other names 2,2-Difluoroacetic acid
Identifiers
CAS Number	381-73-7 ;
3D model (JSmol)	Interactive image;
ChemSpider	10200426;
ECHA InfoCard	100.006.218
PubChem CID	9788;
UNII	ZQK1C95K3N ;
CompTox Dashboard (EPA)	DTXSID50896814 DTXSID2059932, DTXSID50896814 ;
	InChI InChI=1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6) Key: PBWZKZYHONABLN-UHFFFAOYSA-N;
	SMILES C(C(=O)O)(F)F;
Properties
Chemical formula	C2H2F2O2
Molar mass	96.033 g·mol−1
Density	1.526 g/mL
Melting point	−1 °C (30 °F; 272 K)
Boiling point	132–134 °C (270–273 °F; 405–407 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Difluoroacetic acid is a chemical compound with formula CHF₂COOH. It is a dihalogenocarboxylic acid, specifically a structural analog of acetic acid with two of three hydrogen atoms on the alpha carbon replaced with fluorine atoms. In solution, it dissociates to form difluoroacetate ions. Difluoroacetic acid can also be used as direct C-H difluoromethylating reagent.^[2]

References

^ ^a ^b ^c "Difluoroacetic acid". Sigma-Aldrich.
^ Tung, Truong Thanh; Christensen, Søren Brøgger; Nielsen, John (2017). "Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds". Chemistry - A European Journal. 23 (72): 18125–18128. doi:10.1002/chem.201704261. PMID 28945302.

This article about an organic halide is a stub. You can help Wikipedia by expanding it.

[SA-1] "Difluoroacetic acid". Sigma-Aldrich.

[2] Tung, Truong Thanh; Christensen, Søren Brøgger; Nielsen, John (2017). "Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds". Chemistry - A European Journal. 23 (72): 18125–18128. doi:10.1002/chem.201704261. PMID 28945302.

[1]

[2]

See also

References