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Difluoroacetic acid

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Difluoroacetic acid
Names
IUPAC name
2,2-Difluoroacetic acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.006.218 Edit this at Wikidata
  • InChI=1S/C2H2F2O2/c3-1(4)2(5)6/h1H,(H,5,6)
    Key: PBWZKZYHONABLN-UHFFFAOYSA-N
  • C(C(=O)O)(F)F
Properties
C2H2F2O2
Molar mass 96.033 g·mol−1
Density 1.526 g/mL[1]
Melting point −1 °C (30 °F; 272 K)[1]
Boiling point 132–134 °C (270–273 °F; 405–407 K)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Difluoroacetic acid is a chemical compound with formula CHF2COOH. It is a dihalogenocarboxylic acid, specifically a structural analog of acetic acid with two of three hydrogen atoms on the alpha carbon replaced with fluorine atoms. In solution, it dissociates to form difluoroacetate ions. Difluoroacetic acid can also be used as direct C-H difluoromethylating reagent.[2].

See also

References

  1. ^ a b c "Difluoroacetic acid". Sigma-Aldrich.
  2. ^ "Difluoroacetic Acid as a New Reagent for Direct C-H Difluoromethylation of Heteroaromatic Compounds". Chemistry - A European Journal.