Dihydrotanshinone I
Appearance
![]() 2D Structure
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![]() 3D Conformer
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Names | |
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IUPAC name
(1R)-1,6-Dimethyl-1,2-dihydronaphtho[1,2-g][1]benzofuran-10,11-dione
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Systematic IUPAC name
1,6-dimethyl-1,2-dihydrophenanthro[1,2-b]furan-10,11-dione | |
Other names
15,16-dihydrotanshinone I, phenanthro[1,2-b]furan-10,11-dione, 1,2-dihydro-1,6-dimethyl-
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Identifiers | |
3D model (JSmol)
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Abbreviations | DI |
ChemSpider | |
ECHA InfoCard | 100.222.905 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C18H14O3 | |
Molar mass | 278.307 g·mol−1 |
Appearance | Red powder |
Density | 1.32 g/cm3 |
Boiling point | 479.2 °C (894.6 °F; 752.3 K) |
12.9 mg/L (est.) | |
Solubility in ethanol | 1 mg/mL, clear orange to red |
log P | log Kow = 3.93 (est) |
Vapor pressure | 3.41x10−9 mmHg |
Hazards | |
GHS labelling: | |
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Warning | |
H302, H400 | |
P264, P270, P273, P301+P312, P330, P391, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dihydrotanshinone I (DI) is a naturally occurring compound extracted from Salvia miltiorrhiza Bunge, also known as Chinese sage, red sage root, and the Chinese herbal Dan Shen. It belongs to a class of lipophilic abietane biterpenoids[2] and has been reported to have cytotoxicity to a variety of tumor cells.[3] Since they were first discovered, over 40 related compounds and over 50 hydrophilic compounds have been isolated from Dan Shen.[2]
References
- ^ "Dihydrotanshinone I". PubChem. PubChem. Retrieved 31 August 2015.
- ^ a b "HSDB: DIHYDROTANSHINONE I". NIH. Retrieved 1 September 2015.
- ^ Bian, Weipeng; et al. "Dihydrotanshinone I inhibits angiogenesis both in vitro and in vivo". ABBS. Retrieved 31 August 2015.