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E120 usually refers to:
- Carmine, a food colourant with the E number E120
- Unbinilium, also known as eka-radium or simply element 120, a predicted chemical element not yet observed
It may also refer to:
- E120 bomblet, a U.S. Cold War biological cluster bomb sub-munition
- The ICAO aircraft type designator for the Embraer EMB 120 Brasilia
- Juniper E-Series, Broadband Services Router
- KiHa E120, a Japanese train type
- Toyota Corolla (E120), a car
- Acer beTouch E120, a smartphone
- Azorubine (E122)
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