|This article does not cite any sources. (December 2009) (Learn how and when to remove this template message)|
The enterogastric reflex is one of the three extrinsic reflexes of the gastrointestinal tract, the other two being the gastrocolic reflex and the gastroileal reflex. The enterogastric reflex is stimulated in the duodenum by a pH of 3-4 and in the stomach by a pH of 1.5. Upon initiation of the reflex, the release of gastrin by G-cells in the antrum of the stomach is shut off. This in turn inhibits gastric motility and the secretion of gastric acid (HCl).
Emptying inhibitory factors
The stomach's contents are inhibited from emptying into the small intestine by
- duodenal acidic pH
- duodenal distension
- duodenal hypertonicity
- sympathetic stimulation
- intense pain
- increased osmolarity of gastric chyme
Emptying stimulatory factors
The stomach's contents empty through the pylorus, allowing digestion to proceed, when there is
- parasympathetic stimulation
- increased volume and fluidity of gastric contents
- "Nervous System of the Digestive System - Gastrointestinal Reflex Pathways". Boundless. Retrieved 31 March 2016.