Enterovirus cis-acting replication element
|Enterovirus cis-acting replication element|
Enterovirus cis-acting replication element is a small RNA hairpin in the coding region of protein 2C as the site in PV1(M) RNA that is used as the primary template for the in vitro uridylylation. The first step in the replication of the plus-stranded poliovirus RNA is the synthesis of a complementary minus strand. This process is initiated by the covalent attachment of uridine monophosphate (UMP) to the terminal protein VPg, yielding VPgpU and VPgpUpU.
- Paul, AV; Rieder E; Kim DW; van Boom JH; Wimmer E (2000). "Identification of an RNA hairpin in poliovirus RNA that serves as the primary template in the in vitro uridylylation of VPg". J Virol. 74 (22): 10359–10370. doi:10.1128/JVI.74.22.10359-10370.2000. PMC . PMID 11044080.
- Goodfellow, I; Chaudhry Y; Richardson A; Meredith J; Almond JW; Barclay W; Evans DJ (2000). "Identification of a cis-acting replication element within the poliovirus coding region". J Virol. 74 (10): 4590–4600. doi:10.1128/JVI.74.10.4590-4600.2000. PMC . PMID 10775595.
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