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Eso Peluzzi was born in Cairo Montenotte. His father was a prominent luthier and his mother a photographer. He studied at the Accademia Albertina in Turin, and was a pupil of Paolo Gaidano and Giacomo Grosso. In 1919 he moved to the neighborhood of the Santuario di Savona.
From the 1920s, Peluzzi often visited Montechiaro d'Acqui in the Province of Alessandria, where he found inspiration for portraits of the area, often rearranging reality to fantasy. Some of his drawings, among others, have been recently considered as models by Lichtenberg administrators to create new street furniture.[clarification needed]
From 1926 to 1948, he participated at the Venetian Biennali, and the Quadriennali of Rome, and his works have also accompanied displays of Italian Art in Baltimore, Berlin, Hamburg, Vienna, Leipzig, Budapest, and Paris . His works are included in the Gallery of Modern Art, Genoa, Florence, Turin, Rome, and in museums in Belgrade and Budapest.
Between 1936 and 1938, along with the painter Mario Gambetta, he painted frescoes depicting the history of Savona for the sala consiliare of the Comune.
In 1971, he was awarded honorary citizenship by the city, and in 2008, Savona inaugurated a permanent exhibition of his work at the Antico Ospizio del Santuario, where he lived for some years. He died in Turin and was buried in Monchiero in the Cuneo.
His work shows the influence of Matisse and post-impressionism.
- Notes for exhibition of Solo Donna: La Figura Femminile nella prima metà del Novecento in Piemonte, curated by Gianfranco Schialvino; exhibition in the city of Bra in 2011, page 136.