Exosite: Difference between revisions
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An '''exosite''' is a secondary binding site, remote from the active site, on an [[enzyme]] or other [[protein]].<ref>[http://www.ingentaconnect.com/content/bsc/jth/2007/00000005/00000010/art00013 IngentaConnect Manipulation of thrombin exosite I, by ligand-directed covalent m<!-- Bot generated title -->]</ref> |
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This is similar to [[allosteric]] sites, but differs in the fact that, in order for an enzyme to be active, its exosite typically must be occupied.<ref>[http://www.blackwellpublishing.com/isth2003/abstract.asp?id=9231 Congress of the International Society on Thrombosis and Haemostasis<!-- Bot generated title -->]</ref> Exosites have recently become a hot topic in biomedical research as potential drug targets.{{citation needed|date=April 2011}} |
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== References == |
== References == |
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Revision as of 10:54, 27 March 2012
to hell and back to the end of time my love for you hits with a smack the highest mountain i will climb no matter what i love you
References
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