FATE1

FATE1
Identifiers
Aliases	FATE1, CT43, FATE, fetal and adult testis expressed 1
External IDs	OMIM: 300450; HomoloGene: 57202; GeneCards: FATE1; OMA:FATE1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	151,723,194 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; testicle; ; gonad; ; apex of heart; ; deltoid muscle; ; upper respiratory tract; ; duodenum; ; cingulate gyrus; ; anterior cingulate cortex;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; ubiquitin protein ligase binding;
Cellular component	integral component of membrane; membrane; mitochondria-associated endoplasmic reticulum membrane; mitochondrion; mitochondrial outer membrane; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	negative regulation of apoptotic process; negative regulation of mitochondrial calcium ion concentration; apoptotic process; regulation of apoptotic process;
	Sources:Amigo / QuickGO
Orthologs
	89885
	n/a
	ENSG00000147378
	n/a
	Q969F0
	n/a
	NM_033085
	n/a
	NP_149076
	n/a
	Wikidata
View/Edit Human

Fetal and adult testis-expressed transcript protein is a protein that in humans is encoded by the FATE1 gene.^[3]^[4] It is testis-specific in the fetus (aged 6 – 11 weeks). In adults, it is expressed predominantly in the testis, with some expression in the lungs, heart, kidneys, adrenal gland, and throughout the brain.^{[citation needed]}

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000147378 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Olesen C, Larsen NJ, Byskov AG, Harboe TL, Tommerup N (Nov 2001). "Human FATE is a novel X-linked gene expressed in fetal and adult testis". Mol Cell Endocrinol. 184 (1–2): 25–32. doi:10.1016/S0303-7207(01)00666-9. PMID 11694338.
^ "Entrez Gene: FATE1 fetal and adult testis expressed 1".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Olesen C, Hansen C, Bendsen E, et al. (2001). "Identification of human candidate genes for male infertility by digital differential display". Mol. Hum. Reprod. 7 (1): 11–20. doi:10.1093/molehr/7.1.11. PMID 11134355.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Olesen C, Silber J, Eiberg H, et al. (2003). "Mutational analysis of the human FATE gene in 144 infertile men". Hum. Genet. 113 (3): 195–201. doi:10.1007/s00439-003-0974-9. PMID 12811541.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000147378 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11694338-3] Olesen C, Larsen NJ, Byskov AG, Harboe TL, Tommerup N (Nov 2001). "Human FATE is a novel X-linked gene expressed in fetal and adult testis". Mol Cell Endocrinol. 184 (1–2): 25–32. doi:10.1016/S0303-7207(01)00666-9. PMID 11694338.

[entrez-4] "Entrez Gene: FATE1 fetal and adult testis expressed 1".

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References

Further reading