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Glycyrrhizol

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Glycyrrhizol A
Names
IUPAC name
1-Methoxy-2,8-bis-(3-methyl-but-2-enyl)-6H-[1]benzofuro[3,2-c]chromene-3,9-diol
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
  • InChI=1S/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 checkY
    Key: CBPFOSMNDISZLV-UHFFFAOYSA-N checkY
  • InChI=1/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3
    Key: CBPFOSMNDISZLV-UHFFFAOYAJ
  • o2c1c(cc(c(O)c1)C\C=C(/C)C)c3c2c4c(OC)c(c(O)cc4OC3)C\C=C(/C)C
Properties
C26H28O5
Molar mass 420.50 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Glycyrrhizol A is a prenylated pterocarpan, a derivative of isoflavonoids. It is a compound isolated from the root of the Chinese Licorice plant (Glycyrrhiza uralensis).

Recent studies by scientists from UCLA have suggested that these compounds have antibacterial properties.[1] The strongest antibacterial activity was observed against Streptococcus mutans, an organism known to cause tooth decay in humans.

References

  1. ^ He J, Chen L, Shi W, Lu Q-Y (2006). "Antibacterial Compounds from Glycyrrhiza uralensis". Journal of Natural Products. 69 (1): 121–124. doi:10.1021/np058069d. PMID 16441081.


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