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He was briefly bishop of Nîmes, and then bishop of Albi, in 1337, but only for a year, as Pope Benedict XII shortly elevated him to the cardinalate. He was the nephew of Benedict, who as Jacques Fournier had been a bishop of Mirepoix active in hunting heresy in south-west France; and in any case was a countryman and supporter in these activities.
Subsequently he investigated several cases of Franciscan spirituals under suspicion. The major work Liber secretorum eventuum of Joannes de Rupescissa was written to his order. In decisions of an Avignon theological tribune he headed in 1354, Joannes de Rupescissa was cleared; John of Castillon and Francis of Arquata were condemned and burned.
- Guillaume de Court Nouvel, Guglielmo Curti, Guilelmus Curti.
- From 1338 , with the title Ss. Quattro Coronati ; from 1350 as bishop of Frascati.
- Maarten van der Heijden and Bert Roest, FRANCISCAN AUTHORS, 13TH - 18TH CENTURY: A CATALOGUE IN PROGRESS Johannes de Rupescissa Retrieved: 2016-10-22.
- NOT BORED! is an autonomous, situationist-inspired, low-budget, irregularly published journal, Prous Boneta, retrieved: 2016-10-22;[better source needed] see also "Archived copy". Archived from the original on 2007-06-12. Retrieved 2007-06-17.(German).