HIST3H3

H3-4
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2V1D, 2YBP, 2YBS, 3A6N, 3T6R, 4V2W
Identifiers
Aliases	H3-4, H3.4, H3/g, H3FT, H3t, histone cluster 3, H3, histone cluster 3 H3, HIST3H3, H3.4 histone
External IDs	OMIM: 602820 HomoloGene: 133212 GeneCards: H3-4
Gene location (Human)
Chr.	Chromosome 1 (human)
End	228,425,360 bp
RNA expression pattern
	Top expressed in
	right coronary artery; ; canal of the cervix; ; right uterine tube; ; gastric mucosa; ; stromal cell of endometrium; ; urinary bladder; ; vagina; ; ascending aorta; ; myometrium; ; right adrenal gland;
	n/a
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein heterodimerization activity; DNA binding; histone binding; protein binding; nucleosomal DNA binding;
Cellular component	nucleosome; extracellular exosome; nucleus; chromosome; nucleoplasm;
Biological process	negative regulation of protein oligomerization; nucleosome assembly; protein heterotetramerization; double-strand break repair via nonhomologous end joining; telomere capping;
	Sources:Amigo / QuickGO
Orthologs
	8290
	n/a
	ENSG00000168148; ENSG00000285435
	n/a
	Q16695
	n/a
	NM_003493
	n/a
	NP_003484
	n/a
	Wikidata
View/Edit Human

Histone H3.1t is a protein that in humans is encoded by the HIST3H3 gene.^[3]^[4]

References

^ ^a ^b ^c ENSG00000285435 GRCh38: Ensembl release 89: ENSG00000168148, ENSG00000285435 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Albig W, Ebentheuer J, Klobeck G, Kunz J, Doenecke D (Dec 1996). "A solitary human H3 histone gene on chromosome 1". Hum Genet. 97 (4): 486–91. doi:10.1007/BF02267072. PMID 8834248.
^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). "The human and mouse replication-dependent histone genes". Genomics. 80 (5): 487–98. doi:10.1016/S0888-7543(02)96850-3. PMID 12408966.