Hasubanonine

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Hasubanonine
Hasubanonine.svg
Names
Other names
Hasubanonine
Identifiers
3D model (JSmol)
ChemSpider
Properties
C21H27NO5
Molar mass 373.19 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Hasubanonine is a member of the hasubanan family of alkaloids. The alkaloid with an isoquinoline substructure has the molecular formula of C21H27NO5.[1] The enantiomer of the natural product is being studied as a potential painkiller.[2] Hasubanonine is structurally related to the morphinan class of opioid analgesics.

The enantioselective total synthesis of (–)-hasubanonine and related natural products, (−)-runanine, (−)-delavayine, and (+)-periglaucine B were first achieved by Prof. Seth Herzon and co-workers at Yale University in 2011. [3]

References[edit]

  1. ^ Hasubanonine
  2. ^ Deseret News - Chemists hoping to ease pain
  3. ^ Herzon, S. B.; Calandra, N. A.; King, S. M. Angew. Chem. Int. Ed. 2011, 1:5 (12 September 2011), doi:10.1002/anie.201102226