Helvetius is the Roman name for a member of the Gallic tribe known as the Helvetii, or an inhabitant of their territory, Helvetia (now known as Switzerland). It may also refer to:
- a Roman cognomen, typically borne by those of Helvetian origin.
- Helvidius, sometimes written Helvetius, the author of a work written prior to 383 against the belief in the perpetual virginity of Mary.
- Claude Adrien Helvétius (1715–1771), a French philosopher and littérateur.
- Anne-Catherine de Ligniville, Madame Helvétius (1722–1800), the philosopher's wife, who maintained a renowned salon in France in the eighteenth century.
- James Francis Helvetius Hobler (1764-1844).
- Johann Friedrich Schweitzer, also known as John Frederick Helvetius (1625–1709), a Dutch physician and alchemical writer of German extraction.
- a character in The Second Maiden's Tragedy.
- 6972 Helvetius, a main-belt asteroid, discovered in 1992.
- Helvetia, the national personification of Switzerland
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