Humster
A humster is a hybrid cell line made from a hamster oocyte fertilized with human sperm. This is possible due to the unique promiscuity of a hamster ova, which allows it to fuse with non-hamster sperm.[1] It always consists of single cells, and cannot form a multi-cellular being. Humsters are usually destroyed before they divide into two cells; were they left alone to divide, they would still be unviable.[2]
Humsters are routinely created mainly for two reasons:
- To avoid legal issues with working with pure human embryonic stem cell lines.
- To assess the viability of human sperm for in vitro fertilization
Somatic cell hybrids between humans and hamsters or mice have been used for the mapping of various traits since at least the 1970s.[3]
See also[edit]
References[edit]
- ^ Yanagimachi, R.; Yanagimachi, H.; Rogers, B. J. (1976-11-01). "The Use of Zona-Free Animal Ova as a Test-System for the Assessment of the Fertilizing Capacity of Human Spermatozoa". Biology of Reproduction. 15 (4): 471–476. doi:10.1095/biolreprod15.4.471. ISSN 0006-3363.
- ^ Final Report of the Human Embryo Research Panel (Report). Bethesda, MD: National Institutes of Health. 27 September 1994. As cited in Bonnicksen, Andrea (2009). Chimeras, Hybrids, and Interspecies Research Politics and Policymaking. Georgetown University Press. ISBN 9781589015746.
- ^ Griffiths AJ, Miller JH, Suzuki DT, et al. (2000-02-04). "Mapping human genes by using human–rodent somatic cell hybrids". An introduction to genetic analysis (7th ed.). W.H. Freeman. ISBN 0-7167-3520-2. Retrieved 5 March 2019.
- Humans and Hybrids: A Critique of the Western Moral Framework
- Junca et al. (1983) "Evaluation of human sperm fertility by interspecific (human spermatozoa-hamster oocytes) in vitro fertilization." Acta Eur. Fertil. 14, 191-196
Further reading[edit]
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