It is performed by measuring the arterial blood gases of the patient while they breathe room air, then re-measuring the blood gases after the patient has breathed 100% oxygen for 10 minutes.:141 If the cause of the cyanosis is poor oxygen saturation by the lungs, allowing the patient to breathe 100% oxygen will augment the lungs' ability to saturate the blood with oxygen, and the partial pressure of oxygen in the arterial blood will rise (usually above 150 mmHg). However, if the lungs are healthy and already fully saturating the blood that is delivered to them, then supplemental oxygen will have no effect, and the partial pressure of oxygen will usually remain below 100 mmHg. In this case, the cyanosis is most likely due to blood that moves from the systemic veins to the systemic arteries via a right-to-left shunt without ever going through the lungs.:141
- Fyler, edited by John F. Keane, James E. Lock, Donald C. (2006). Nadas' pediatric cardiology (2nd ed.). Philadelphia [u.a.]: Saunders [u.a.] ISBN 978-1-4160-2390-6.
- "When Do Cyanotic Congenital Heart Diseases Present?". Pediatric Education. 2006-01-23. Retrieved 2011-10-26.
- Dr. Ira Shah (2006-02-15). "How To Manage Blue Baby Maha Neocon 2005 pediatric oncall". Pediatriconcall.com. Archived from the original on 2012-08-27. Retrieved 2011-10-26.