IGH@
Appearance
IGH | |||||||||||||||||||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | IGH, IGD1, IGH.1@, IGH@, IGHD@, IGHDY1, IGHJ, IGHJ@, IGHV, IGHV@, immunoglobulin heavy locus, IgH locus | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 146910, 147010, 147070; GeneCards: IGH; OMA:IGH - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
| |||||||||||||||||||||||||||||||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
|
Immunoglobulin heavy locus, also known as IGH, is a region on human chromosome 14 that contains a gene for the heavy chains of human antibodies (or immunoglobulins).[2]
Nomenclature
Symbols for variable (V) immunoglobulin genes start with IGHV and include two or three numbers separated by dashes. Examples:
- IGHV1-2, IGHV1-3, …, IGHV1-69-2, IGHV2-5, …, IGHV7-4-1
Symbols for diversity (D) immunoglobulin genes start with IGHD and include two numbers separated by dashes. Examples:
- IGHD1-1, IGHD1-7, …, IGHD7-27
Symbols for joining (J) immunoglobulin genes:
- IGHJ1, IGHJ2, IGHJ3, IGHJ4, IGHJ5, IGHJ6
Symbols for constant region (C) immunoglobulin genes:
See also
References
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: IGH immunoglobulin heavy locus".
- ^ "Gene Family: Immunoglobulin heavy locus at 14q32.33 (IGH)". HGNC: HUGO Gene Nomenclature Committee.
Further reading