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Infantilism may refer to:
- In psychology
- Paraphilic infantilism, a paraphilia involving the desire to wear diapers and/or fantasies of a return to infancy
- Psychosexual infantilism, a concept in psychosexual development introduced by Sigmund Freud
- In a more general sense and in colloquial expressions - childlike behavior in adults, particularly lack of judgement and poor ability to make conclusions based on logical reasoning as well as actions driven more by immediate impressions and impulses rather than by rationale. Depending on degree of expression can range from mental disorder, to behavioral disorder or simply psychological makeup and personality trait of otherwise healthy person.
- In medicine
- Infantilism (physiological disorder) obsolete use of the term for some developmental disorders and disabilities
- Infantilism, also known as infantile speech, a speech disorder in which early speech stages persist beyond the age they are normally expected to fade
- Hypothalamic infantilism-obesity, or sexual infantilism, synonyms for adiposogenital dystrophy
- Delayed puberty, delayed sexual development symptomatic of several medical syndromes
- Diaper fetishism, a paraphilic attraction to wearing diapers which does not involve fantasies of childlike behavior
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