IFT27

IFT27
Identifiers
Aliases	IFT27, BBS19, RABL4, RAYL, intraflagellar transport 27, FAP156
External IDs	OMIM: 615870 MGI: 1914292 HomoloGene: 4998 GeneCards: IFT27
Gene location (Human)
Chr.	Chromosome 22 (human)
End	36,776,256 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	78,058,307 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; anterior pituitary; ; caudate nucleus; ; nucleus accumbens; ; right lobe of thyroid gland; ; right adrenal gland; ; amygdala; ; putamen; ; left lobe of thyroid gland;
	Top expressed in
	internal carotid artery; ; external carotid artery; ; medial ganglionic eminence; ; facial motor nucleus; ; condyle; ; fossa; ; maxillary prominence; ; spermatocyte; ; medullary collecting duct; ; barrel cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; GTPase activity;
Cellular component	cell projection; motile cilium; sperm principal piece; sperm midpiece; ciliary tip; centrosome; intraciliary transport particle B; endosome; Golgi apparatus; cilium; cytoplasm; sperm flagellum; membrane; intracellular anatomical structure;
Biological process	smoothened signaling pathway; protein transport; intracellular protein transport; intraciliary transport; cochlea development; inner ear receptor cell stereocilium organization; intraciliary transport involved in cilium assembly; kidney development; spermatogenesis; Rab protein signal transduction; cell differentiation; signal transduction; small GTPase mediated signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	11020
	67042
	ENSG00000100360
	ENSMUSG00000016637
	Q9BW83
	Q9D0P8
	NM_001177701; NM_001177702; NM_006860; NM_001363003
	NM_025931
	NP_001171172; NP_006851; NP_001349932
	NP_080207
	Wikidata
View/Edit Human	View/Edit Mouse

Intraflagellar transport 27 is a protein that in humans is encoded by the IFT27 gene. ^[5]

Function[edit]

This gene encodes a GTP-binding protein that is a core component of the intraflagellar transport complex B. Characterization of the similar Chlamydomonas protein indicates a function in cell cycle control. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000100360 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000016637 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Intraflagellar transport 27". Retrieved 2018-05-22.

Function[edit]

References[edit]

Further reading[edit]