Izuna can refer to:
- The Japanese name for the least weasel and its subspecies.
- Mount Izuna in Japan.
- The Izuna Shugen cult which originated on this mountain, which worships a god in the form of a tengu named Izuna-gongen.
- A fox-sorcery practice which is part of this cult, which utilizes creatures such as the kuda-gitsune.
- Izuna: Legend of the Unemployed Ninja, a Nintendo DS game.
- Izuna 2: The Unemployed Ninja Returns, sequel to the above game
- Izuna, a character from the Guilty Gear series of video games.
- Izuna Uchiha, the deceased younger brother of Madara Uchiha from Naruto.
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