Jesse Lee may refer to:
- Jesse Lee (Methodist) (1758–1816), American Methodist Episcopal clergyman and pioneer
- Jesse Lee (politician) (born 1979), White House Online Programs Director under the Barack Obama Administration
- Jesse Lee (singer) (born 1987), American country music artist
- Jesse Lee, a gunslinger played by Mario Van Peebles in the 1993 film Posse.
- Jesse Soffer (born 1984), American actor sometimes credited as "Jesse Lee"
- Jesse Lee (Tinder Slayer) (born 1995), New Zealand National Tinder Slays of the Year (2016)
- All pages with a title containing Jesse Lee
- Jessica Lee (disambiguation)
- Jessie Lee (disambiguation)
- Jess Lee (disambiguation)
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