Before her retirement in 2003 Clark was responsible for the development of a program of research in community health nursing and primary health care at Swansea University. Her special interest is the development and use of standardized nomenclatures to describe nursing practice, in particular in primary health care. In 1990 she left the NHS and went into higher education as Professor of Nursing to start a new School of Nursing at Middlesex University. In 1997 she "went home to Wales" as the first professor of nursing at Swansea University
During the 1990s she was consultant to the International Council of Nurses' project to develop an International Classification of Nursing Practice (ICNP). She is also deputy president of the Welsh Nursing Academy.
Clark qualified as a nurse at University College Hospital, London, after obtaining an honours degree in Classics at the University of London. She then worked as a health visitor, and remained in community nursing as a manager, professor, and political advocate for nearly 40 years. She obtained her MPhil degree at the University of Reading in 1972, and her Ph.D from South Bank Polytechnic in 1985.
She has also been heavily involved in nursing at an international level. Following the break-up of the Soviet Union she worked to help develop nursing leadership in Kazakhstan and Romania. She is a visiting professor at the University of Primorska, Slovenia. She is a frequent speaker at international conferences, has participated in numerous international task groups and workshops, has acted as consultant to WHO and ICN, and has represented the UK on ICN and European Union committees.. She is an active member of Sigma Theta Tau International, and was instrumental in establishing the Upsilon-Xi Chapter in Wales  - the first in the UK and only the third in Europe and was STTI Board member from 2009-2011 She is committed to the goal of making STTI an "intentionally global" organisation.
- "Professor Dame June Clark". Royal College of Nursing. Retrieved 2008-10-29.
- "Welsh Nursing Academy Council". Retrieved 2011-12-28.
- "Professor Dame June Clark" (PDF). Swansea University. Retrieved 5 January 2012.
- "Upsilon-Xi Leaders". Retrieved 2011-12-28.
- "STTI June Clark Biography". Retrieved 2011-12-28.
- Clark, June (2004-05-05). "Nursing nursing". The Guardian (London). Retrieved 2008-10-29.
- "Nurse leader under fire". BBC News (BBC). 2002-06-14. Retrieved 2008-10-29.