K10 transport/localisation element (TLS)

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K10 transport/localisation element (TLS)
RF00207.jpg
Identifiers
SymbolK10_TLS
RfamRF00207
Other data
RNA typeCis-reg
Domain(s)Eukaryota
SOSO:0005836
PDB structuresPDBe

The K10 transport/localisation element (TLS) is a 44 nucleotide K10 TLS regulatory element from Drosophila melanogaster. K10 TLS is responsible for the transport and anterior localisation of K10 mRNA and acts to establish dorsoventral polarity in the oocyte.[1][2] It was discovered by Julia Serano.

References[edit]

  1. ^ Serano TL, Cohen RS (November 1995). "A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA". Development. 121 (11): 3809–3818. PMID 8582290.
  2. ^ Guillemin K, Williams T, Krasnow MA (September 2001). "A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila". Nature Cell Biology. 3 (9): 848–851. doi:10.1038/ncb0901-848. PMID 11533666.

External links[edit]