K10 transport/localisation element (TLS)

From Wikipedia, the free encyclopedia
Jump to: navigation, search
K10 transport/localisation element (TLS)
Symbol K10_TLS
Rfam RF00207
Other data
RNA type Cis-reg
Domain(s) Eukaryota
SO 0005836

The K10 transport/localisation element (TLS) is a 44 nucleotide K10 TLS regulatory element from Drosophila melanogaster. K10 TLS is responsible for the transport and anterior localisation of K10 mRNA and acts to establish dorsoventral polarity in the oocyte.[1][2] It was discovered by Julia Serano.


  1. ^ Serano, TL; Cohen RS (1995). "A small predicted stem-loop structure mediates oocyte localization of Drosophila K10 mRNA". Development. 121 (11): 3809–3818. PMID 8582290. 
  2. ^ Guillemin, K; Williams T; Krasnow MA (2001). "A nuclear lamin is required for cytoplasmic organization and egg polarity in Drosophila". Nat Cell Biol. 3 (9): 848–851. PMID 11533666. doi:10.1038/ncb0901-848. 

External links[edit]