KLK2

KLK2
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	4NFE, 4NFF
Identifiers
Aliases	KLK2, KLK2A2, hGK-1, hK2, kallikrein related peptidase 2
External IDs	OMIM: 147960; HomoloGene: 124422; GeneCards: KLK2; OMA:KLK2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	50,880,567 bp
RNA expression pattern
	Top expressed in
	prostate; ; right testis; ; left testis; ; male germ cell; ; sperm; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; testicle; ; thymus; ; urethra;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peptidase activity; serine-type peptidase activity; serine-type endopeptidase activity; hydrolase activity;
Cellular component	extracellular region; extracellular exosome; secretory granule;
Biological process	extracellular matrix disassembly; proteolysis; regulation of systemic arterial blood pressure; zymogen activation;
	Sources:Amigo / QuickGO
Orthologs
	3817
	n/a
	ENSG00000167751
	n/a
	P20151
	n/a
	NM_001002231; NM_001002232; NM_001256080; NM_005551
	n/a
	NP_001002231; NP_001243009; NP_005542
	n/a
	Wikidata
View/Edit Human

Kallikrein-2 is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue.^[3]^[4]^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000167751 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Riegman PH, Vlietstra RJ, Klaassen P, van der Korput JA, Geurts van Kessel A, Romijn JC, Trapman J (May 1989). "The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19". FEBS Lett. 247 (1): 123–126. doi:10.1016/0014-5793(89)81253-0. PMID 2468530.
^ Lundwall A, Band V, Blaber M, Clements JA, Courty Y, Diamandis EP, Fritz H, Lilja H, Malm J, Maltais LJ, Olsson AY, Petraki C, Scorilas A, Sotiropoulou G, Stenman UH, Stephan C, Talieri M, Yousef GM (Jun 2006). "A comprehensive nomenclature for serine proteases with homology to tissue kallikreins". Biol Chem. 387 (6): 637–641. doi:10.1515/BC.2006.082. PMID 16800724.
^ Diamandis, Eleftherios P.; Deperthes, David; Lundwall, Åke (Jun 2006). "Proceedings of the 1st International Symposium on Kallikreins, Lausanne, Switzerland, September 1-3 , 2005". Biol Chem. 387 (6): 635–636. doi:10.1515/BC.2006.081. PMID 16800723.
^ "Entrez Gene: KLK2 Kallikrein-related peptidase 2".

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