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Kameleon may refer to:

  • Kameleon, A web design format created by Kameleon Web Designs-Dayton Ohio
  • Kameleon, a Pseudonymization product developed by Mastek Ltd.
  • Kamelion, a fictitious Android during the Peter Davison era of Doctor Who
  • Cameleon (protein), a genetically encoded calcium sensor created by Roger Y. Tsien and coworkers.
  • K-Meleon, a Gecko-based web browser for Windows
  • Chameleon: To Dye For!, a 2006 puzzle video game for portables, released as Chameleon in North America and Kameleon in Europe