Early in his career George played with McKinney's Cotton Pickers (1933) and Cecil Lee. Later in the 1930s he spent time in the Jeter-Pillars Orchestra and then in the orchestras of Teddy Wilson (1939–40) and Lionel Hampton (1941-42). He served in the Army in 1942-43, then moved to California and played with Stan Kenton (1943), Benny Carter (1944), Count Basie (1945), and Happy Johnson (1946). He led his own group on record in 1945-46, and played in sessions led by Charles Mingus, Slim Gaillard, Oscar Pettiford, Dinah Washington, and Lucky Thompson. George retired from music after the late 1940s due to ill health.
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With Count Basie
- The Original American Decca Recordings (GRP, 1937-39 )
With Stan Kenton
- Stan Kenton's Milestones (Capitol, 1943-47 )
- Stan Kenton Classics (Capitol, 1944-47 )
- The Kenton Era (Capitol, 1940–54, )
- Karl George at Allmusic
- Leonard Feather and Ira Gitler, The Biographical Encyclopedia of Music. Oxford, 1999, p. 251.
- Karl George at WorldCat
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